Drug Information
Drug General Information | |||||
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Drug ID |
D0SJ2Q
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Former ID |
DNC006677
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Drug Name |
OLEANOLIC_ACID
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540267] | ||
Structure |
Download2D MOL |
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Formula |
C30H48O3
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InChI |
InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1
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InChIKey |
MIJYXULNPSFWEK-GTOFXWBISA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
411432, 606099, 8140048, 8157593, 12013877, 14931343, 16612754, 22396103, 24898021, 26725302, 29204449, 29228987, 48483988, 49999299, 53253218, 53788193, 57326261, 57654491, 85297334, 92298723, 92465252, 92711005, 93576683, 96023600, 103324264, 104082596, 104323458, 118048745, 124558746, 124800067, 125312644, 126524541, 126631301, 126657657, 126664253, 128600272, 134343882, 134976838, 136353287, 137006891, 137186946, 142252735, 152090835, 162223020, 163614423, 164786710, 175267875, 175607979, 178100342, 179150511
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Target and Pathway | |||||
Target(s) | mRNA of Protein tyrosine phosphatase-1B | Target Info | Inhibitor | [530332] | |
Glycogen phosphorylase, muscle form | Target Info | Inhibitor | [529507] | ||
DNA polymerase | Target Info | Inhibitor | [525684] | ||
BioCyc Pathway | Glycogenolysis | ||||
NetPath Pathway | FSH Signaling Pathway | ||||
Pathway Interaction Database | Insulin Pathway | ||||
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | |||||
Signaling events mediated by PTP1B | |||||
Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
Signaling events mediated by TCPTP | |||||
IGF1 pathway | |||||
EGF receptor (ErbB1) signaling pathway | |||||
Posttranslational regulation of adherens junction stability and dissassembly | |||||
PDGFR-beta signaling pathway | |||||
N-cadherin signaling events | |||||
References | |||||
Ref 525684 | J Nat Prod. 1999 Dec;62(12):1624-6.DNA polymerase beta inhibitors from Baeckea gunniana. | ||||
Ref 529507 | J Med Chem. 2008 Jun 26;51(12):3540-54. Epub 2008 Jun 3.Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies. | ||||
Ref 530332 | J Nat Prod. 2009 Sep;72(9):1620-6.Chemical Constituents of the Roots of Euphorbia micractina. |
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