Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0FK0A
|
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| Former ID |
DNC002578
|
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| Drug Name |
2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [551374] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C12H14N6
|
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| Canonical SMILES |
C1C(NC2=C(N1)N=C(N=C2N)N)C3=CC=CC=C3
|
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| InChI |
1S/C12H14N6/c13-10-9-11(18-12(14)17-10)15-6-8(16-9)7-4-2-1-3-5-7/h1-5,8,16H,6H2,(H5,13,14,15,17,18)/t8-/m0/s1
|
||||
| InChIKey |
VEKRIXRQADJFAG-QMMMGPOBSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Nitric-oxide synthase, endothelial | Target Info | Inhibitor | [551374] | |
| BioCyc Pathway | Citrulline-nitric oxide cycle | ||||
| NetPath Pathway | Wnt Signaling Pathway | ||||
| Pathway Interaction Database | Plasma membrane estrogen receptor signaling | ||||
| Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||||
| Angiopoietin receptor Tie2-mediated signaling | |||||
| Thromboxane A2 receptor signaling | |||||
| SHP2 signaling | |||||
| VEGFR1 specific signals | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| PAR1-mediated thrombin signaling events | |||||
| References | |||||
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