TTD | Drug: D03DEJ

Drug General Information
Drug ID	D03DEJ
Former ID	DIB018992
Drug Name	BMS614
Synonyms	BMS 614; BMS-614
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539709]
Structure		Download 2D MOL
Formula	C29H24N2O3
InChI	InChI=1S/C29H24N2O3/c1-29(2)14-13-23(21-15-19-5-3-4-6-26(19)30-17-21)24-16-20(9-12-25(24)29)27(32)31-22-10-7-18(8-11-22)28(33)34/h3-13,15-17H,14H2,1-2H3,(H,31,32)(H,33,34)
InChIKey	WGLMBRZXZDAQHP-UHFFFAOYSA-N
PubChem Compound ID	445091
PubChem Substance ID	837265, 10299631, 36887910, 50948432, 104633543, 118043378, 129578080, 135650004, 140274230, 174496040, 208265529, 232446631, 241376567, 249617942, 249815169, 252157434
Target and Pathway
Target(s)	Retinoic acid receptor alpha	Target Info	Antagonist	[526251]
KEGG Pathway	Pathways in cancer
	Transcriptional misregulation in cancer
	Acute myeloid leukemia
Pathway Interaction Database	Retinoic acid receptors-mediated signaling
Reactome	Nuclear Receptor transcription pathway
WikiPathways	Vitamin A and Carotenoid Metabolism
	Nuclear Receptors in Lipid Metabolism and Toxicity
	Integrated Pancreatic Cancer Pathway
	Adipogenesis
	Nuclear Receptors
References
Ref 539709	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2643).
Ref 526251	Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. Nature. 2002 Jan 10;415(6868):187-92.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information