Drug General Information
Drug ID
D0U4HM
Former ID
DIB021074
Drug Name
TPMPA
Synonyms
(1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467666]
Structure
Download
2D MOL

3D MOL

Formula
C6H12NO2P
InChI
InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)
InChIKey
MFUKVPOVVKKLRQ-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) GABAA receptor rho2 subunit Target Info Antagonist [543821]
GABAA receptor rho3 subunit Target Info Antagonist [543822]
GABAA receptor rho1 subunit Target Info Antagonist [543820]
References
Ref 467666(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4328).
Ref 543820(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 420).
Ref 543821(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 421).
Ref 543822(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 422).

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