Drug Information
Drug General Information | |||||
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Drug ID |
D0W2UK
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Former ID |
DIB020039
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Drug Name |
IK-862
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Synonyms |
IK862; IK 862; compound 32
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529692] | ||
Structure |
Download2D MOL |
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Formula |
C25H27N3O4
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InChI |
InChI=1S/C25H27N3O4/c1-16-14-18(21-6-4-5-7-22(21)26-16)15-32-20-10-8-19(9-11-20)25(3)12-13-28(24(25)30)17(2)23(29)27-31/h4-11,14,17,31H,12-13,15H2,1-3H3,(H,27,29)/t17-,25+/m1/s1
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InChIKey |
YDMIPBHQKFOFQW-NSYGIPOTSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | ADAM 33 | Target Info | Inhibitor | [529692] | |
ADAM 17 | Target Info | Inhibitor | [529692] | ||
Pathway Interaction Database | ErbB4 signaling events | ||||
TNF receptor signaling pathway | |||||
p75(NTR)-mediated signaling | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Collagen degradation | |||||
Regulated proteolysis of p75NTR | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 t(7 | |||||
M1580_K2555) Translocation Mutant | |||||
Constitutive Signaling by NOTCH1 HD Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
TNF signaling | |||||
Growth hormone receptor signaling | |||||
References |
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