Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R9CH
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| Former ID |
DNC007526
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| Drug Name |
ZK-810388
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528872] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C23H20Cl3N5O4S
|
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| Canonical SMILES |
CN(CC1=CSC(=C1Cl)C(=O)NC2=C(C=C(C=C2C(=O)NC3=NC=C(C=C3)<br />Cl)Cl)OC)C4=NCCO4
|
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| InChI |
1S/C23H20Cl3N5O4S/c1-31(23-27-5-6-35-23)10-12-11-36-20(18(12)26)22(33)30-19-15(7-14(25)8-16(19)34-2)21(32)29-17-4-3-13(24)9-28-17/h3-4,7-9,11H,5-6,10H2,1-2H3,(H,30,33)(H,28,29,32)
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| InChIKey |
FBXIHZSULWMHJY-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Plasma kallikrein | Target Info | Inhibitor | [528872] | |
| Coagulation factor Xa | Target Info | Inhibitor | [528872] | ||
| NetPath Pathway | AndrogenReceptor Signaling Pathway | ||||
| PANTHER Pathway | Blood coagulationP00011:Blood coagulation | ||||
| Pathway Interaction Database | Beta2 integrin cell surface interactions | ||||
| PathWhiz Pathway | CoagulationPW000562:Coagulation | ||||
| Reactome | Intrinsic Pathway of Fibrin Clot Formation | ||||
| Activation of Matrix MetalloproteinasesR-HSA-140834:Extrinsic Pathway of Fibrin Clot Formation | |||||
| Common Pathway of Fibrin Clot Formation | |||||
| Gamma-carboxylation of protein precursors | |||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
| References | |||||
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