Drug General Information
Drug ID	D01PWO
Former ID	DNC012942
Drug Name	4-(2-nitrobenzylthio)-2-aminobutanoic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527946]
Structure		Download 2D MOL 3D MOL
Formula	C11H14N2O4S
Canonical SMILES	C1=CC=C(C(=C1)CSCCC(C(=O)O)N)[N+](=O)[O-]
InChI	1S/C11H14N2O4S/c12-9(11(14)15)5-6-18-7-8-3-1-2-4-10(8)13(16)17/h1-4,9H,5-7,12H2,(H,14,15)
InChIKey	QZOGSZKBBMQKMN-UHFFFAOYSA-N
PubChem Compound ID	44408226
Target and Pathway
Target(s)	Voltage-dependent calcium channel subunit alpha-2/delta-1	Target Info	Inhibitor	[527946]
KEGG Pathway	MAPK signaling pathway
	Cardiac muscle contraction
	Adrenergic signaling in cardiomyocytes
	Oxytocin signaling pathway
	Hypertrophic cardiomyopathy (HCM)
	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
	Dilated cardiomyopathy
PANTHER Pathway	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
WikiPathways	Arrhythmogenic Right Ventricular Cardiomyopathy
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 527946	Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. Epub 2005 Dec 27.Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.
Ref 527946	Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. Epub 2005 Dec 27.Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.

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