Drug Information

Drug General Information
Drug ID
D0G8KA
Former ID
DIB020690
Drug Name
Pfizer compound 11
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529445], [541124]
Structure
Download
2D MOL
Formula
C24H18ClF3N4O3
InChI
InChI=1S/C24H18ClF3N4O3/c1-15-14-22(32(31-15)20-8-4-2-6-18(20)25)34-21-9-5-3-7-19(21)30-23(33)29-16-10-12-17(13-11-16)35-24(26,27)28/h2-14H,1H3,(H2,29,30,33)
InChIKey
SAIPZPCGTLOMFE-UHFFFAOYSA-N
PubChem Compound ID
24958668
PubChem Substance ID
56256538, 57487599, 103563510, 141846860, 160852424, 178102429, 198962316, 223370249, 224218106, 230790802, 246718833
Target and Pathway
Target(s) P2Y purinoceptor 1 Target Info Antagonist [529445]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Platelet activation
Reactome G alpha (q) signalling events
P2Y receptors
ADP signalling through P2Y purinoceptor 1
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Signal amplification
GPCR ligand binding
GPCR downstream signaling
References
Ref 529445Bioorg Med Chem Lett. 2008 Jun 1;18(11):3338-43. Epub 2008 Apr 15.P2Y1 receptor antagonists as novel antithrombotic agents.
Ref 541124(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5804).
Ref 529445Bioorg Med Chem Lett. 2008 Jun 1;18(11):3338-43. Epub 2008 Apr 15.P2Y1 receptor antagonists as novel antithrombotic agents.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.