Drug Information
Drug General Information | |||||
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Drug ID |
D02TSN
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Former ID |
DIB018925
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Drug Name |
AZ20
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Synonyms |
AZ-20; AZ 20; compound 6 [PMID: 46244454]
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [532224] | ||
Structure |
Download2D MOL |
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Formula |
C21H24N4O3S
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InChI |
InChI=1S/C21H24N4O3S/c1-14-13-28-11-10-25(14)19-12-18(21(7-8-21)29(2,26)27)23-20(24-19)16-4-3-5-17-15(16)6-9-22-17/h3-6,9,12,14,22H,7-8,10-11,13H2,1-2H3/t14-/m1/s1
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InChIKey |
SCGCBAAYLFTIJU-CQSZACIVSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Serine threonine protein kinase ATR | Target Info | Inhibitor | [532224] | |
PANTHER Pathway | p53 pathway | ||||
p53 pathway feedback loops 2 | |||||
Pathway Interaction Database | Fanconi anemia pathway | ||||
ATR signaling pathway | |||||
Signaling events mediated by TCPTP | |||||
Circadian rhythm pathway | |||||
BARD1 signaling events | |||||
p53 pathway | |||||
Reactome | Meiotic synapsis | ||||
Activation of ATR in response to replication stress | |||||
Regulation of HSF1-mediated heat shock response | |||||
HDR through Single Strand Annealing (SSA) | |||||
Processing of DNA double-strand break ends | |||||
Presynaptic phase of homologous DNA pairing and strand exchange | |||||
G2/M DNA damage checkpoint | |||||
References |
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