TTD | Drug: D08BXO

Drug General Information
Drug ID	D08BXO
Former ID	DIB020443
Drug Name	MRS2950
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541129]
Structure		Download 2D MOL
Formula	C20H20Cl2N4O2S
InChI	InChI=1S/C20H20Cl2N4O2S/c1-12-13(2)25-28-19(12)26-29(3,4)16-8-5-14(6-9-16)23-20(27)24-15-7-10-17(21)18(22)11-15/h5-11,26H,3-4H2,1-2H3,(H2,23,24,27)
InChIKey	ZRNSPTWPSVBOTC-UHFFFAOYSA-N
PubChem Compound ID	73755158
PubChem Substance ID	178102434
Target and Pathway
Target(s)	P2Y purinoceptor 1	Target Info	Antagonist	[531978]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	G alpha (q) signalling events
	P2Y receptors
	ADP signalling through P2Y purinoceptor 1
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541129	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5809).
Ref 531978	Virtual screening leads to the discovery of novel non-nucleotide P2Y??receptor antagonists. Bioorg Med Chem. 2012 Sep 1;20(17):5254-61.

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Drug Information