Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Y6ST
|
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| Former ID |
DIB020890
|
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| Drug Name |
SAG
|
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| Synonyms |
1-stearoyl-2-arachidonoyl-sn-glycerol
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [539565] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C41H72O5
|
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| InChI |
InChI=1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,17,19,22,24,28,30,39,42H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3/b13-11-,19-17-,24-22-,30-28-/t39-/m0/s1
|
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| InChIKey |
NSXLMTYRMFVYNT-IUJDHQGTSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | TRPC2 | Target Info | Activator | [526896] | |
| Short transient receptor potential channel 6 | Target Info | Activator | [534828] | ||
| PANTHER Pathway | Alzheimer disease-presenilin pathway | ||||
| Pathway Interaction Database | Endothelins | ||||
| Nephrin/Neph1 signaling in the kidney podocyte | |||||
| EPO signaling pathway | |||||
| PAR1-mediated thrombin signaling events | |||||
| References | |||||
| Ref 526896 | A diacylglycerol-gated cation channel in vomeronasal neuron dendrites is impaired in TRPC2 mutant mice: mechanism of pheromone transduction. Neuron. 2003 Oct 30;40(3):551-61. | ||||
| Ref 534828 | Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature. 1999 Jan 21;397(6716):259-63. | ||||
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