TTD | Drug: D0Y6FA

Drug General Information
Drug ID	D0Y6FA
Former ID	DIB019652
Drug Name	CP734432
Synonyms	CP 734432; CP-734432
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540640]
Structure		Download 2D MOL
Formula	C23H25F3NO4S-
InChI	InChI=1S/C23H26F3NO4S/c24-23(25,26)16-4-1-3-15(13-16)14-18(28)8-6-17-7-11-21(29)27(17)12-2-5-19-9-10-20(32-19)22(30)31/h1,3-4,9-10,13,17-18,28H,2,5-8,11-12,14H2,(H,30,31)/p-1/t17-,18+/m0/s1
InChIKey	JYZXGURJKNAFPT-ZWKOTPCHSA-M
PubChem Compound ID	73755071
PubChem Substance ID	178100863
Target and Pathway
Target(s)	Prostaglandin E2 receptor, EP4 subtype	Target Info	Agonist	[530142]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Inflammatory mediator regulation of TRP channels
	Renin secretion
	Pathways in cancer
NetPath Pathway	FSH Signaling Pathway
	IL2 Signaling Pathway
	IL4 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
Reactome	Prostanoid ligand receptors
Reactome	G alpha (s) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Vitamin D Receptor Pathway
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540640	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4039).
Ref 530142	Ocular pharmacokinetics and hypotensive activity of PF-04475270, an EP4 prostaglandin agonist in preclinical models. Exp Eye Res. 2009 Nov;89(5):608-17.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information