Drug General Information
Drug ID
D0V1PD
Former ID
DIB019638
Drug Name
cooling agent 10
Synonyms
(-)-menthoxypropane-1,2-diol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539591]
Structure
Download
2D MOL
Formula
C13H26O3
InChI
InChI=1S/C13H26O3/c1-9(2)12-5-4-10(3)6-13(12)16-8-11(15)7-14/h9-15H,4-8H2,1-3H3
InChIKey
MDVYIGJINBYKOM-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) TRPM8 protein Target Info Activator [526953]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 539591(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2463).
Ref 526953Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45. Epub 2004Feb 2.

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