Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0A1MW
|
||||
Former ID |
DIB018752
|
||||
Drug Name |
aconitine
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Discovery agent | Investigative | [539689] | ||
Structure |
Download2D MOL |
||||
Formula |
C34H47NO11
|
||||
InChI |
InChI=1S/C34H47NO11/c1-7-35-15-31(16-41-3)20(37)13-21(42-4)33-19-14-32(40)28(45-30(39)18-11-9-8-10-12-18)22(19)34(46-17(2)36,27(38)29(32)44-6)23(26(33)35)24(43-5)25(31)33/h8-12,19-29,37-38,40H,7,13-16H2,1-6H3/t19-,20-,21+,22-,23+,24+,25-,26?,27+,28-,29+,31+,32-,33+,34-/m1/s1
|
||||
InChIKey |
XFSBVAOIAHNAPC-XTHSEXKGSA-N
|
||||
PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Sodium channel protein type 2 subunit alpha | Target Info | Activator | [533513] | |
Sodium channel protein type 5 subunit alpha | Target Info | Activator | [532584] | ||
KEGG Pathway | Adrenergic signaling in cardiomyocytes | ||||
PathWhiz Pathway | Muscle/Heart Contraction | ||||
Reactome | Interaction between L1 and Ankyrins | ||||
References | |||||
Ref 532584 | Properties of aconitine-modified sodium channels in single cells of mouse ventricular myocardium. Gen Physiol Biophys. 1986 Oct;5(5):473-84. | ||||
Ref 533513 | Binding of batrachotoxinin A 20-alpha-benzoate to a receptor site associated with sodium channels in synaptic nerve ending particles. J Biol Chem. 1981 Sep 10;256(17):8922-7. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.