Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W0WL
|
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| Former ID |
DNC006513
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| Drug Name |
1,6-bis(4'-methylaminophenyl)-hexa-1,3,5-triene
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528161] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H22N2
|
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| Canonical SMILES |
CNC1=CC=C(C=C1)C=CC=CC=CC2=CC=C(C=C2)NC
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| InChI |
1S/C20H22N2/c1-21-19-13-9-17(10-14-19)7-5-3-4-6-8-18-11-15-20(22-2)16-12-18/h3-16,21-22H,1-2H3/b4-3+,7-5+,8-6+
|
||||
| InChIKey |
SWZSFUMMCHKHMM-OKWWDJPNSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528161] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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