Drug Information

Drug General Information
Drug ID
D08LFC
Former ID
DNC014555
Drug Name
CGP-35024
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551250]
Structure
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2D MOL

3D MOL
Formula
C4H12NO2P
InChI
InChI=1S/C4H12NO2P/c1-8(6,7)4-2-3-5/h2-5H2,1H3,(H,6,7)
InChIKey
NHVRIDDXGZPJTJ-UHFFFAOYSA-N
PubChem Compound ID
5230
PubChem Substance ID
5608484, 7978903, 8153213, 11110690, 11113473, 15219048, 25746534, 26751694, 29224286, 47216900, 47365331, 47662433, 47885537, 48185114, 50064309, 50104385, 53786182, 57322666, 77292575, 85208918, 90513940, 103065080, 103080796, 103334994, 104308634, 117626404, 117733988, 124749445, 124879060, 124879061, 124879062, 124879063, 125660989, 128704542, 131751337, 134224389, 134351760, 135081534, 135649731, 137008675, 140384422, 162223784, 164848763, 166270618, 179148822, 179419315, 204360310, 224018692, 226677152, 241181641
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [551250]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 551250Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity, Bioorg. Med. Chem. Lett. 3(4):515-518 (1993).
Ref 551250Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity, Bioorg. Med. Chem. Lett. 3(4):515-518 (1993).

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