Drug Information
Drug General Information | |||||
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Drug ID |
D0H8QQ
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Former ID |
DIB018378
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Drug Name |
[3H]PGD2
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Synonyms |
[3H]11-dehydroprostaglandin F2-alpha; [3H]prostaglandin D2; [3H]-PGD2
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539191] | ||
Structure |
Download2D MOL |
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Formula |
C20H32O5
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InChI |
InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1
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InChIKey |
BHMBVRSPMRCCGG-OUTUXVNYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
3964, 583767, 4265955, 7889816, 7980420, 8143213, 10300216, 12012669, 15496745, 24898605, 26754808, 26754809, 36890302, 46504574, 47515086, 48258962, 49700655, 50026788, 50110785, 53788536, 57404870, 77723738, 92297650, 92309902, 99300816, 99302334, 104046434, 104639469, 123099371, 126524027, 127277724, 127277725, 127277726, 127277727, 127277728, 127277729, 127277730, 127277731, 127277732, 127277733, 127346781, 127346782, 127346783, 135001740, 135651538, 135651568, 137005673, 142697392, 143486570, 160965276
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Target and Pathway | |||||
Target(s) | Putative G-protein coupled receptor 44 | Target Info | Agonist | [527971] | |
Prostaglandin D2 receptor | Target Info | Agonist | [528126] | ||
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
Pathway Interaction Database | Thromboxane A2 receptor signaling | ||||
PathWhiz Pathway | Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 | ||||
References | |||||
Ref 527971 | On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2. Mol Pharmacol. 2006 Apr;69(4):1441-53. Epub 2006 Jan 17. | ||||
Ref 528126 | GW627368X ((N-{2-[4-(4,9-diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)phenyl]acetyl} benzene sulphonamide): a novel, potent and selective prostanoid EP4 receptor antagonist. Br J Pharmacol. 2006 Jun;148(3):326-39. |
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