TTD | Drug: D0KF2P

Drug General Information
Drug ID	D0KF2P
Former ID	DIB019490
Drug Name	compound 4
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[532047], [541198]
Structure		Download 2D MOL
Formula	C29H37N5O9
InChI	InChI=1S/C29H37N5O9/c1-3-41-27(39)29(13-8-14-29)43-23-19-22(31-34(23)20-9-6-5-7-10-20)25(37)30-21(11-12-24(35)36)26(38)32-15-17-33(18-16-32)28(40)42-4-2/h5-7,9-10,19,21H,3-4,8,11-18H2,1-2H3,(H,30,37)(H,35,36)/t21-/m0/s1
InChIKey	HPSHQEAEJMOGDO-NRFANRHFSA-N
PubChem Compound ID	44126037
PubChem Substance ID	84977909, 87208700, 163317729, 163346169, 178102528, 224477806, 227383116, 245673911
Target and Pathway
Target(s)	P2Y purinoceptor 12	Target Info	Antagonist	[532047]
KEGG Pathway	Platelet activation
Reactome	P2Y receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 532047	Identification of high-affinity P2Y??? antagonists based on a phenylpyrazole glutamic acid piperazine backbone. J Med Chem. 2012 Oct 25;55(20):8615-29.
Ref 541198	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5905).
Ref 532047	Identification of high-affinity P2Y??? antagonists based on a phenylpyrazole glutamic acid piperazine backbone. J Med Chem. 2012 Oct 25;55(20):8615-29.

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Drug Information