Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01RQK
|
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| Former ID |
DIB018484
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| Drug Name |
15-deoxy-Delta12,14-PGJ2
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| Synonyms |
15d-Delta12,14-PGJ2; 15deoxy-delta-12,14-PGJ2; LS-125843
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [539177] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C20H28O3
|
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| InChI |
InChI=1S/C20H28O3/c1-2-3-4-5-6-10-13-18-17(15-16-19(18)21)12-9-7-8-11-14-20(22)23/h6-7,9-10,13,15-17H,2-5,8,11-12,14H2,1H3,(H,22,23)/b9-7-,10-6-,18-13+/t17-/m0/s1
|
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| InChIKey |
VHRUMKCAEVRUBK-WKELIDJCSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Putative G-protein coupled receptor 44 | Target Info | Agonist | [526611] | |
| Prostaglandin D2 receptor | Target Info | Agonist | [534620] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | Thromboxane A2 receptor signaling | ||||
| PathWhiz Pathway | Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 | ||||
| References | |||||
| Ref 526611 | Expression and molecular pharmacology of the mouse CRTH2 receptor. J Pharmacol Exp Ther. 2003 Aug;306(2):463-70. Epub 2003 Apr 29. | ||||
| Ref 534620 | Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist. Br J Pharmacol. 1998 Apr;123(7):1317-24. | ||||
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