Drug Information

Drug General Information
Drug ID
D05REQ
Former ID
DNC011268
Drug Name
3-(3-aminocyclopentyl)-1H-indole-5-carbonitrile
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531220]
Structure
Download
2D MOL

3D MOL
Formula
C14H15N3
Canonical SMILES
C1CC(CC1C2=CNC3=C2C=C(C=C3)C#N)N
InChI
1S/C14H15N3/c15-7-9-1-4-14-12(5-9)13(8-17-14)10-2-3-11(16)6-10/h1,4-5,8,10-11,17H,2-3,6,16H2
InChIKey
MBZJCLUPDBZVMZ-UHFFFAOYSA-N
PubChem Compound ID
22139473
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Inhibitor [531220]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 531220J Med Chem. 2010 Nov 11;53(21):7564-72.Conformationally restricted homotryptamines. Part 7: 3-cis-(3-aminocyclopentyl)indoles as potent selective serotonin reuptake inhibitors.
Ref 531220J Med Chem. 2010 Nov 11;53(21):7564-72.Conformationally restricted homotryptamines. Part 7: 3-cis-(3-aminocyclopentyl)indoles as potent selective serotonin reuptake inhibitors.

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