Drug Information
Drug General Information | |||||
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Drug ID |
D0F2XQ
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Former ID |
DAP000567
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Drug Name |
Fludarabine
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Synonyms |
FaraA; Fludarabina; Fludarabinum; Fluradosa; Fludarabina [Spanish]; Fludarabine [INN]; Fludarabinum [Latin]; SQ Fludarabine; Fludara, Fludarabine; Fludarabine (INN); Fluradosa (TN); F-Ara-A; (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 2-F-ara-A; 2-Fluoro Ara-A; 2-Fluoro-9-beta-D-arabinofuranosyladenine; 9-beta-D-Arabinofuranosyl-2-fluoroadenine; 9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine; 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro-(9CI)
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anticancer Agents
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Company |
Genzyme Corp
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Structure |
Download2D MOL |
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Formula |
C10H12FN5O4
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InChI |
InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1
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InChIKey |
HBUBKKRHXORPQB-FJFJXFQQSA-N
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CAS Number |
CAS 75607-67-9
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PubChem Compound ID | |||||
PubChem Substance ID |
855645, 7979234, 9268240, 12015425, 14751067, 15222429, 49865029, 53790210, 56310845, 57408458, 71840321, 74951141, 96024661, 99437182, 99453172, 103588722, 104170131, 113529123, 117527505, 118048763, 121362454, 123121326, 124757293, 124800219, 125164097, 128038069, 130399360, 131378849, 134994031, 135684141, 135697967, 135723536, 136342497, 136367939, 136375530, 137000684, 141858050, 144115985, 144206348, 144206969, 151994330, 152055900, 152344067, 162011966, 162036224, 163072527, 164216431, 166831392, 170464764, 172080756
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SuperDrug ATC ID |
L01BB05
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SuperDrug CAS ID |
cas=021679141
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Target and Pathway | |||||
Target(s) | Adenosine deaminase | Target Info | Inhibitor | [535008] | |
NetPath Pathway | TCR Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
PANTHER Pathway | Adenine and hypoxanthine salvage pathway | ||||
PathWhiz Pathway | Purine Metabolism | ||||
Reactome | Purine salvage | ||||
WikiPathways | Metabolism of nucleotides | ||||
References | |||||
Ref 468033 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4802). | ||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. |
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