Drug General Information
Drug ID
D0HR8H
Former ID
DNC002828
Drug Name
(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL

Formula
C4H5IN2O2
Canonical SMILES
C1C(C(=O)NC(=O)N1)I
InChI
1S/C4H5IN2O2/c5-2-1-6-4(9)7-3(2)8/h2H,1H2,(H2,6,7,8,9)/t2-/m0/s1
InChIKey
YGKCTZPSAOUUMT-REOHCLBHSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Dihydropyrimidine dehydrogenase [NADP+] Target Info Inhibitor [551393]
BioCyc Pathway Pyrimidine ribonucleosides degradation
Thymine degradation
Uracil degradation
KEGG Pathway Pyrimidine metabolism
beta-Alanine metabolism
Pantothenate and CoA biosynthesis
Drug metabolism - other enzymes
Metabolic pathways
PANTHER Pathway Pyrimidine Metabolism
PathWhiz Pathway Beta-Alanine Metabolism
Pyrimidine Metabolism
WikiPathways Metabolism of nucleotides
Fluoropyrimidine Activity
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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