Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0H8TE
|
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| Former ID |
DNC004054
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| Drug Name |
Z-Arg-Leu-Val-Agly-Ala-Gly-NH2
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [526417] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C31H51N11O8
|
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| Canonical SMILES |
CC(C)CC(C(=O)NC(C(C)C)C(=O)NNC(=O)NC(C)C(=O)NCC(=O)N)NC<br />(=O)C(CCCN=C(N)N)NC(=O)OCC1=CC=CC=C1
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| InChI |
1S/C31H51N11O8/c1-17(2)14-22(27(46)40-24(18(3)4)28(47)41-42-30(48)37-19(5)25(44)36-15-23(32)43)38-26(45)21(12-9-13-35-29(33)34)39-31(49)50-16-20-10-7-6-8-11-20/h6-8,10-11,17-19,21-22,24H,9,12-16H2,1-5H3,(H2,32,43)(H,36,44)(H,38,45)(H,39,49)(H,40,46)(H,41,47)(H4,33,34,35)(H2,37,42,48)
|
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| InChIKey |
QPGAIIGEIAEEEV-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cathepsin B | Target Info | Inhibitor | [526417] | |
| Cathepsin K | Target Info | Inhibitor | [526417] | ||
| Reactome | Collagen degradation | ||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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