Drug Information

Drug General Information
Drug ID
D0Y4DA
Former ID
DNC002642
Drug Name
Alpha-Difluoromethylornithine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
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2D MOL

3D MOL
Formula
C6H12F2N2O2
Canonical SMILES
C(CC(C(F)F)(C(=O)O)N)CN
InChI
1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)
InChIKey
VLCYCQAOQCDTCN-UHFFFAOYSA-N
PubChem Compound ID
3009
PubChem Substance ID
10198, 575150, 597889, 5340424, 7979149, 8151916, 15195195, 26697290, 29222157, 47736604, 48259361, 48413613, 48415938, 49857314, 50068858, 50111043, 57321552, 75030139, 90341137, 96024579, 103937549, 104302261, 123094710, 123121561, 124749707, 124879830, 125675814, 126666031, 126670951, 126685284, 129490554, 132563807, 134338563, 134339956, 135010753, 136342494, 137006071, 142212859, 162178731, 162221551, 162356694, 163134100, 164814590, 164823944, 171578146, 174006789, 178101866, 179117032, 184547857, 184605807
Target and Pathway
Target(s) Ornithine decarboxylase Target Info Inhibitor [551393]
BioCyc Pathway Putrescine biosynthesis I
NetPath Pathway TCR Signaling Pathway
IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Ornithine degradation
CCKR signaling map ST
Pathway Interaction Database Validated targets of C-MYC transcriptional activation
PathWhiz Pathway Spermidine and Spermine Biosynthesis
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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