Drug General Information
Drug ID
D06GRW
Former ID
DNC011698
Drug Name
N-Hydroxy-N-methyl-2,3,3-triphenyl-acrylamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532087]
Structure
Download
2D MOL

3D MOL

Formula
C22H19NO2
Canonical SMILES
CN(C(=O)C(=C(C1=CC=CC=C1)C2=CC=CC=C2)C3=CC=CC=C3)O
InChI
1S/C22H19NO2/c1-23(25)22(24)21(19-15-9-4-10-16-19)20(17-11-5-2-6-12-17)18-13-7-3-8-14-18/h2-16,25H,1H3
InChIKey
ORTZIDPYVDIVSI-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [532087]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 532087J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.
Ref 532087J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.

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