Drug Information

Drug General Information
Drug ID
D05JAH
Former ID
DNC005040
Drug Name
4-Carbazol-9-yl-butyric acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527208]
Structure
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2D MOL

3D MOL
Formula
C16H15NO2
Canonical SMILES
C1=CC=C2C(=C1)C3=CC=CC=C3N2CCCC(=O)O
InChI
1S/C16H15NO2/c18-16(19)10-5-11-17-14-8-3-1-6-12(14)13-7-2-4-9-15(13)17/h1-4,6-9H,5,10-11H2,(H,18,19)
InChIKey
HQAKVYGASUTQHH-UHFFFAOYSA-N
PubChem Compound ID
448769
Target and Pathway
Target(s) Fatty acid-binding protein, adipocyte Target Info Inhibitor [527208]
Fatty acid-bindingprotein, epidermal Target Info Inhibitor [527208]
KEGG Pathway PPAR signaling pathwayhsa03320:PPAR signaling pathway
NetPath Pathway TCR Signaling PathwayNetPath_13:IL1 Signaling Pathway
Pathway Interaction Database AP-1 transcription factor network
Reactome Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
Transcriptional regulation of white adipocyte differentiationR-HSA-163560:Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
WikiPathways Lipid digestion, mobilization, and transport
Transcriptional Regulation of White Adipocyte Differentiation
References
Ref 527208Bioorg Med Chem Lett. 2004 Sep 6;14(17):4445-8.Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target.
Ref 527208Bioorg Med Chem Lett. 2004 Sep 6;14(17):4445-8.Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target.

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