Drug General Information
Drug ID	D0C7GB
Former ID	DNC013011
Drug Name	1-(piperidin-3-ylmethyl)pyridin-2(1H)-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528157]
Structure		Download 2D MOL 3D MOL
Formula	C11H16N2O
Canonical SMILES	C1CC(CNC1)CN2C=CC=CC2=O
InChI	1S/C11H16N2O/c14-11-5-1-2-7-13(11)9-10-4-3-6-12-8-10/h1-2,5,7,10,12H,3-4,6,8-9H2
InChIKey	CRXGPVZZFUWGAF-UHFFFAOYSA-N
PubChem Compound ID	44410533
Target and Pathway
Target(s)	Neuronal acetylcholinereceptor subunit alpha-2	Target Info	Inhibitor	[528157]
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Nicotinic acetylcholine receptor signaling pathway
Reactome	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
	Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 528157	J Med Chem. 2006 May 4;49(9):2673-6.Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.
Ref 528157	J Med Chem. 2006 May 4;49(9):2673-6.Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.

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