Drug Information
Drug General Information | |||||
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Drug ID |
DX5UNS
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Drug Name |
GW673715X
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Synonyms |
GW673715X; CHEMBL243907
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C24H23N5O4
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Canonical SMILES |
CCc1cccc(NC(=O)Nc2ccc(Oc3ccc4nc(NC(=O)OC)[nH]c4c3)cc2)c1
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InChI |
InChI=1S/C24H23N5O4/c1-3-15-5-4-6-17(13-15)26-23(30)25-16-7-9-18(10-8-16)33-19-11-12-20-21(14-19)28-22(27-20)29-24(31)32-2/h4-14H,3H2,1-2H3,(H2,25,26,30)(H2,27,28,29,31)
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InChIKey |
IDBPJJQGJZOVMW-UHFFFAOYSA-N
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Target and Pathway | |||||
Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
Angiopoietin 1 receptor | Target Info | [1587926] | |||
NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
PANTHER Pathway | Angiogenesis | ||||
VEGF signaling pathwayP00005:Angiogenesis | |||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
Beta3 integrin cell surface interactions | |||||
Signaling events mediated by TCPTP | |||||
SHP2 signaling | |||||
S1P1 pathway | |||||
VEGF and VEGFR signaling network | |||||
Integrins in angiogenesis | |||||
Signaling events mediated by VEGFR1 and VEGFR2 | |||||
Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
References |
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