Drug General Information
Drug ID
DX3P6V
Drug Name
4'-{[3-(4-Nitro-benzyl)-3H-imidazol-4-ylmethyl]-amino}-[1,1';2',1'']terphenyl-3-carboxylic acid 26 (FTI-2325)
Synonyms
FTI-2325; CHEMBL55484
Indication Discovery agent Investigative [1587926]
Formula
C30H24N4O4
Canonical SMILES
OC(=O)c1cccc(c1)c2ccc(NCc3cncn3Cc4ccc(cc4)[N+](=O)[O-])cc2c5ccccc5
InChI
InChI=1S/C30H24N4O4/c35-30(36)24-8-4-7-23(15-24)28-14-11-25(16-29(28)22-5-2-1-3-6-22)32-18-27-17-31-20-33(27)19-21-9-12-26(13-10-21)34(37)38/h1-17,20,32H,18-19H2,(H,35,36)
InChIKey
SEKKPFKIZQTNBV-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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