Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXQC6D
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| Drug Name |
amino(4-(2-(3-carboxyoxirane-2-carboxamido)-4-methylpentanamido)butylamino)methaniminium
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| Synonyms |
E-64; CHEMBL189382
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C15H27N5O5
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)C1OC1C(=O)O)C(=O)NCCCCNC(=N)N
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| InChI |
InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10?,11?/m0/s1
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| InChIKey |
LTLYEAJONXGNFG-WHXUTIOJSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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