Drug Information
| Drug General Information | |||||
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| Drug ID |
DXF6SX
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| Drug Name |
rac-9-(cyclohexylmethyl)-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one
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| Synonyms |
CHEMBL1085292
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C32H36N4O2
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| Canonical SMILES |
Cn1cc2c(CCc3c2c4C(=O)NCc4c5c6cc(ccc6n(CC7CCCCC7)c35)C8CCCCO8)n1
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| InChI |
InChI=1S/C32H36N4O2/c1-35-18-24-25(34-35)12-11-21-28(24)30-23(16-33-32(30)37)29-22-15-20(27-9-5-6-14-38-27)10-13-26(22)36(31(21)29)17-19-7-3-2-4-8-19/h10,13,15,18-19,27H,2-9,11-12,14,16-17H2,1H3,(H,33,37)
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| InChIKey |
YOSNZLGNAZKSBX-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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