Drug Information
| Drug General Information | |||||
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| Drug ID |
DXA1QB
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| Drug Name |
rac-9-(2-ethoxyethyl)-5-methyl-12-(tetrahydro-2H-pyran-2-yl)-5,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one
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| Synonyms |
CHEMBL1082756
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H32N4O3
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| Canonical SMILES |
CCOCCn1c2ccc(cc2c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c13)C7CCCCO7
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| InChI |
InChI=1S/C29H32N4O3/c1-3-35-13-11-33-23-10-7-17(24-6-4-5-12-36-24)14-19(23)26-20-15-30-29(34)27(20)25-18(28(26)33)8-9-22-21(25)16-32(2)31-22/h7,10,14,16,24H,3-6,8-9,11-13,15H2,1-2H3,(H,30,34)
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| InChIKey |
ASSVMZXJIAJLTL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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