Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXA3UN
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| Drug Name |
N-Cyanomethyl-3-cyclobutyl-2-[4'-(4-methyl-piperazin-1-yl)-biphenyl-3-yl]-propionamide
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| Synonyms |
CHEMBL122043
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H32N4O
|
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| Canonical SMILES |
CN1CCN(CC1)c2ccc(cc2)c3cccc(c3)C(CC4CCC4)C(=O)NCC#N
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| InChI |
InChI=1S/C26H32N4O/c1-29-14-16-30(17-15-29)24-10-8-21(9-11-24)22-6-3-7-23(19-22)25(18-20-4-2-5-20)26(31)28-13-12-27/h3,6-11,19-20,25H,2,4-5,13-18H2,1H3,(H,28,31)
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| InChIKey |
TYUMDJNJIRAFAF-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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