Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6KRJ
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| Drug Name |
N4-(3-bromophenyl)-6-(2-methylbenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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| Synonyms |
CHEMBL1095464
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H18BrN5
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| Canonical SMILES |
Cc1ccccc1Cc2cc3c(Nc4cccc(Br)c4)nc(N)nc3[nH]2
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| InChI |
InChI=1S/C20H18BrN5/c1-12-5-2-3-6-13(12)9-16-11-17-18(25-20(22)26-19(17)24-16)23-15-8-4-7-14(21)10-15/h2-8,10-11H,9H2,1H3,(H4,22,23,24,25,26)
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| InChIKey |
KMDRWXNIHZDMQA-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Epidermal growth factor receptor III | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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