Drug Information
| Drug General Information | |||||
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| Drug ID |
DX3GTP
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| Drug Name |
N-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}furan-2-carboxamide
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| Synonyms |
CHEMBL425109
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H25N5O3
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| Canonical SMILES |
CCCn1c2ccc(NC(=O)c3occc3)cc2c4c5CNC(=O)c5c6c(CCc7nn(C)cc67)c14
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| InChI |
InChI=1S/C28H25N5O3/c1-3-10-33-21-9-6-15(30-27(34)22-5-4-11-36-22)12-17(21)24-18-13-29-28(35)25(18)23-16(26(24)33)7-8-20-19(23)14-32(2)31-20/h4-6,9,11-12,14H,3,7-8,10,13H2,1-2H3,(H,29,35)(H,30,34)
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| InChIKey |
MBHBUKNNPIOLLK-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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