Drug Information
Drug General Information | |||||
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Drug ID |
DX6KWY
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Drug Name |
N-[(3R)-1-cyano-3-pyrrolidinyl]-4-fluorobenzamide
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Synonyms |
CHEMBL1672423
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C12H12FN3O
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Canonical SMILES |
Fc1ccc(cc1)C(=O)N[C@@H]2CCN(C2)C#N
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InChI |
InChI=1S/C12H12FN3O/c13-10-3-1-9(2-4-10)12(17)15-11-5-6-16(7-11)8-14/h1-4,11H,5-7H2,(H,15,17)/t11-/m1/s1
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InChIKey |
MWHXRJQRAIXADX-LLVKDONJSA-N
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Target and Pathway | |||||
Target(s) | Cathepsin K | Target Info | [1587926] | ||
Cathepsin B | Target Info | [1587926] | |||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix Metalloproteinases | |||||
Trafficking and processing of endosomal TLR | |||||
MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentation | |||||
WikiPathways | RANKL/RANK Signaling Pathway | ||||
Osteoclast Signaling | |||||
References |
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