Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8VXD
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| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-morpholinothiazol-4-yl)benzamide
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| Synonyms |
CHEMBL199358
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H27N5O3S
|
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| Canonical SMILES |
O=C(NC1(CCCCC1)C(=O)NCC#N)c2ccc(cc2)c3csc(n3)N4CCOCC4
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| InChI |
InChI=1S/C23H27N5O3S/c24-10-11-25-21(30)23(8-2-1-3-9-23)27-20(29)18-6-4-17(5-7-18)19-16-32-22(26-19)28-12-14-31-15-13-28/h4-7,16H,1-3,8-9,11-15H2,(H,25,30)(H,27,29)
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| InChIKey |
TYJLGELUBBAGKK-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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