Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4XSC
|
||||
| Drug Name |
methyl N-(5-(4-((3-(trifluoromethyl)phenyl)aminothiocarbonylamino)phenoxy)-1H-benzimidazol-2-yl)carbamate
|
||||
| Synonyms |
CHEMBL244287
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H18F3N5O3S
|
||||
| Canonical SMILES |
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=S)Nc4cccc(c4)C(F)(F)F)cc3)cc2[nH]1
|
||||
| InChI |
InChI=1S/C23H18F3N5O3S/c1-33-22(32)31-20-29-18-10-9-17(12-19(18)30-20)34-16-7-5-14(6-8-16)27-21(35)28-15-4-2-3-13(11-15)23(24,25)26/h2-12H,1H3,(H2,27,28,35)(H2,29,30,31,32)
|
||||
| InChIKey |
UXYOQWHGYMKOQZ-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.