Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8CJL
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| Drug Name |
D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-Pro(4-O-propyl)-pro(2,3-dibenzo)-arg
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| Synonyms |
CHEMBL2370159
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C57H87N19O14S
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| Canonical SMILES |
CCCO[C@H]1C[C@H](N(C1)C(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](N)CCCN=C(N)N)c4cccs4)C(=O)N5Cc6ccccc6C[C@H]5C(=O)N[C@@H](CCCN=C(N)N)C(=O)O
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| InChI |
InChI=1S/C57H87N19O14S/c1-2-21-90-34-25-42(53(87)74-27-32-11-4-3-10-31(32)23-40(74)48(82)70-37(54(88)89)14-7-19-67-57(63)64)76(29-34)51(85)38(30-77)71-49(83)45(43-16-9-22-91-43)72-44(79)26-68-47(81)41-24-33(78)28-75(41)52(86)39-15-8-20-73(39)50(84)36(13-6-18-66-56(61)62)69-46(80)35(58)12-5-17-65-55(59)60/h3-4,9-11,16,22,33-42,45,77-78H,2,5-8,12-15,17-21,23-30,58H2,1H3,(H,68,81)(H,69,80)(H,70,82)(H,71,83)(H,72,79)(H,88,89)(H4,59,60,65)(H4,61,62,66)(H4,63,64,67)/t33-,34-,35+,36-,37-,38-,39-,40-,41-,42-,45-/m0/s1
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| InChIKey |
KULRZBJHHZWTME-JTXPGYAFSA-N
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| Target and Pathway | |||||
| Target(s) | B1 bradykinin receptor | Target Info | [1587926] | ||
| B2 bradykinin receptor | Target Info | [1587926] | |||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Complement and coagulation cascades | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| Regulation of actin cytoskeleton | |||||
| Pathways in cancerhsa04020:Calcium signaling pathway | |||||
| cGMP-PKG signaling pathway | |||||
| Sphingolipid signaling pathway | |||||
| Endocrine and other factor-regulated calcium reabsorption | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Pathways in cancer | |||||
| Pathway Interaction Database | Direct p53 effectors | ||||
| Validated transcriptional targets of deltaNp63 isoforms | |||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| ACE Inhibitor Pathway | |||||
| Regulation of Actin Cytoskeleton | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Vitamin D Receptor Pathway | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP554:ACE Inhibitor Pathway | |||||
| Nifedipine Activity | |||||
| GPCR downstream signaling | |||||
| References | |||||
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