Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXA44G
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| Drug Name |
Acetic acid (2S,3S)-3-[(1-benzyloxycarbonylamino-cyclopentanecarbonyl)-amino]-4-oxo-azetidin-2-yl ester
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| Synonyms |
CHEMBL62453
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C19H23N3O6
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| Canonical SMILES |
CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)C2(CCCC2)NC(=O)OCc3ccccc3
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| InChI |
InChI=1S/C19H23N3O6/c1-12(23)28-16-14(15(24)21-16)20-17(25)19(9-5-6-10-19)22-18(26)27-11-13-7-3-2-4-8-13/h2-4,7-8,14,16H,5-6,9-11H2,1H3,(H,20,25)(H,21,24)(H,22,26)/t14-,16+/m1/s1
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| InChIKey |
FUOXCWBCJJDEKN-ZBFHGGJFSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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