Drug Information
| Drug General Information | |||||
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| Drug ID |
DX6CSH
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| Drug Name |
9-isobutyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one
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| Synonyms |
CHEMBL1085294
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H32N4O2
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| Canonical SMILES |
CC(C)Cn1c2ccc(cc2c3c4CNC(=O)c4c5c(CCc6c5cnn6C)c13)C7CCCCO7
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| InChI |
InChI=1S/C29H32N4O2/c1-16(2)15-33-23-9-7-17(24-6-4-5-11-35-24)12-19(23)26-21-13-30-29(34)27(21)25-18(28(26)33)8-10-22-20(25)14-31-32(22)3/h7,9,12,14,16,24H,4-6,8,10-11,13,15H2,1-3H3,(H,30,34)
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| InChIKey |
RBIBLTVKXKUJGZ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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