Drug Information

Drug General Information
Drug ID
DXO9EU
Drug Name
8-Dimethylcarbamoylmethyl-3-(4-iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Synonyms
CHEMBL2112890
Indication Discovery agent Investigative [1587926]
Formula
C19H25IN2O3
Canonical SMILES
COC(=O)[C@@H]1C2CCC(C[C@@H]1c3ccc(I)cc3)N2CC(=O)N(C)C
InChI
InChI=1S/C19H25IN2O3/c1-21(2)17(23)11-22-14-8-9-16(22)18(19(24)25-3)15(10-14)12-4-6-13(20)7-5-12/h4-7,14-16,18H,8-11H2,1-3H3/t14?,15-,16?,18+/m1/s1
InChIKey
XPCJTQWBQHOTOA-CSKOPFHVSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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