Drug Information

Drug General Information
Drug ID
DXD5KJ
Drug Name
6-[(4'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-5-(4-trifluoromethoxy-phenyl)-1,2-dihydro-pyridine-3-carbonitrile
Synonyms
CHEMBL338695
Indication Discovery agent Investigative [1587926]
Formula
C33H23ClF3N5O3
Canonical SMILES
CN1C(=C(C=C(C#N)C1=O)c2ccc(OC(F)(F)F)cc2)COC(c3ccc(C#N)c(c3)c4ccc(Cl)cc4)c5cncn5C
InChI
InChI=1S/C33H23ClF3N5O3/c1-41-19-40-17-29(41)31(22-3-4-23(15-38)27(13-22)20-5-9-25(34)10-6-20)44-18-30-28(14-24(16-39)32(43)42(30)2)21-7-11-26(12-8-21)45-33(35,36)37/h3-14,17,19,31H,18H2,1-2H3
InChIKey
AQTMMHDZTUQGJD-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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