Drug Information

Drug General Information
Drug ID
DXI7ZW
Drug Name
5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(2,3-dimethyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
Synonyms
CHEMBL131116
Indication Discovery agent Investigative [1587926]
Formula
C27H22ClN5O2
Canonical SMILES
CN1C(=C(C=C(C#N)C1=O)c2cccc(Cl)c2)COC(c3ccc(cc3)C#N)c4cnc(C)n4C
InChI
InChI=1S/C27H22ClN5O2/c1-17-31-15-24(32(17)2)26(19-9-7-18(13-29)8-10-19)35-16-25-23(20-5-4-6-22(28)11-20)12-21(14-30)27(34)33(25)3/h4-12,15,26H,16H2,1-3H3
InChIKey
JGXPXXUUXXPAIZ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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