Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXI9EW
|
||||
| Drug Name |
4-methyl-3-(3-(pyrimidin-4-yl)pyridin-2-ylamino)-N-(4-(trifluoromethyl)phenyl)benzamide
|
||||
| Synonyms |
CHEMBL222067
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H18F3N5O
|
||||
| Canonical SMILES |
Cc1ccc(cc1Nc2ncccc2c3ccncn3)C(=O)Nc4ccc(cc4)C(F)(F)F
|
||||
| InChI |
InChI=1S/C24H18F3N5O/c1-15-4-5-16(23(33)31-18-8-6-17(7-9-18)24(25,26)27)13-21(15)32-22-19(3-2-11-29-22)20-10-12-28-14-30-20/h2-14H,1H3,(H,29,32)(H,31,33)
|
||||
| InChIKey |
JQSZIQAUXOKNJP-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.