Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXVO2C
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| Drug Name |
4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)benzamide
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| Synonyms |
CHEMBL218576
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H29F3N6O2
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| Canonical SMILES |
CNc1nccc(n1)c2cccnc2Oc3cc(ccc3C)C(=O)Nc4cc(ccc4N5CCCCC5)C(F)(F)F
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| InChI |
InChI=1S/C30H29F3N6O2/c1-19-8-9-20(17-26(19)41-28-22(7-6-13-35-28)23-12-14-36-29(34-2)38-23)27(40)37-24-18-21(30(31,32)33)10-11-25(24)39-15-4-3-5-16-39/h6-14,17-18H,3-5,15-16H2,1-2H3,(H,37,40)(H,34,36,38)
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| InChIKey |
OJRMOHAWDGZYFB-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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