Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXG3IF
|
||||
| Drug Name |
4-methyl-3-(2-(quinolin-3-yl)ethynyl)-N-(3-(trifluoromethyl)-phenyl)benzamide
|
||||
| Synonyms |
CHEMBL219584
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H17F3N2O
|
||||
| Canonical SMILES |
Cc1ccc(cc1C#Cc2cnc3ccccc3c2)C(=O)Nc4cccc(c4)C(F)(F)F
|
||||
| InChI |
InChI=1S/C26H17F3N2O/c1-17-9-11-21(25(32)31-23-7-4-6-22(15-23)26(27,28)29)14-19(17)12-10-18-13-20-5-2-3-8-24(20)30-16-18/h2-9,11,13-16H,1H3,(H,31,32)
|
||||
| InChIKey |
NKKSIIYIDSJFSX-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.