Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6DAO
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| Drug Name |
4-Amino-7-cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
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| Synonyms |
CHEMBL305748
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H22N4O3
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| Canonical SMILES |
Nc1ncnc2c1c(c3ccc(Oc4ccccc4)cc3)c(C(=O)O)n2C5CCCC5
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| InChI |
InChI=1S/C24H22N4O3/c25-22-20-19(15-10-12-18(13-11-15)31-17-8-2-1-3-9-17)21(24(29)30)28(16-6-4-5-7-16)23(20)27-14-26-22/h1-3,8-14,16H,4-7H2,(H,29,30)(H2,25,26,27)
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| InChIKey |
FPIOJWKCVYGQDH-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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