Drug Information

Drug General Information
Drug ID
DXE8QD
Drug Name
4-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid tert-butylamide
Synonyms
CHEMBL171005
Indication Discovery agent Investigative [1587926]
Formula
C30H40ClN5O2
Canonical SMILES
CC(C)(C)NC(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)CC1
InChI
InChI=1S/C30H40ClN5O2/c1-30(2,3)33-29(38)36-13-10-21(11-14-36)19-26(37)34-15-17-35(18-16-34)28-25-9-8-24(31)20-23(25)7-6-22-5-4-12-32-27(22)28/h4-5,8-9,12,20-21,28H,6-7,10-11,13-19H2,1-3H3,(H,33,38)
InChIKey
OWASIDDNULCWSC-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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