Drug Information

Drug General Information
Drug ID
DXI5N2
Drug Name
4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid methylamide
Synonyms
CHEMBL88713
Indication Discovery agent Investigative [1587926]
Formula
C28H33Br2ClN4O2
Canonical SMILES
CNC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]3c4ncc(Br)cc4CCc5cc(Cl)cc(Br)c35)CC1
InChI
InChI=1S/C28H33Br2ClN4O2/c1-32-28(37)35-8-4-17(5-9-35)12-24(36)34-10-6-18(7-11-34)26-25-19(14-22(31)15-23(25)30)2-3-20-13-21(29)16-33-27(20)26/h13-18,26H,2-12H2,1H3,(H,32,37)/t26-/m1/s1
InChIKey
FJEFQPVMMYHHJX-AREMUKBSSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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